In a study involving data from 18,883 subjects 12 years of age and older, low vitamin D status was associated with increased odds of recent upper respiratory tract infection (URTI). While 24% of subjects with 25(OH)D levels less than 10 ng/mL were found to have had a recent URTI, 20% of those with 25(OH)D levels between 10 and less than 30 ng/mL were found to have a recent URTI, compared to only 17% of those with 25(OH)D levels of 30 ng/mL or greater. The
median serum 25(OH)D for subjects with a recent URTI was 29 ng/mL. After adjusting for potential confounders, low 25(OH)D levels were still found to be associated with recent URTI (OR=1.36), with a greater association found in persons with asthma and chronic obstructive pulmonary disease (OR=5.67; OR=2.26, respectively). The authors
conclude, “Randomized controlled trials are warranted to explore the effects of vitamin D supplementation on RTI.”
“Association between serum 25-hydroxyvitamin D level and upper respiratory tract infection in the
Third National Health and Nutrition Examination Survey,” Ginde AA, Mansbach JM, Camargo CA Jr, Arch Intern Med, 2009; 169(4): 384-90. (Address: Emergency Medicine Network, Massachusetts General Hospital, 326 Cambridge Street, Boston, MA 02114, USA).
Source Vitasearch.com 37818